2D-3D Registration

The typical application of 2D-3D registration is to align the real-time 2D fluoroscope frames with pre-operative 3D CT volume. The knowledge of 3D positioning is valuable information during surgical intervention.

Generally speaking, we need to estimate 4 quaternions parameters for rotation (with 3 degree of freedom)  3D pose estimation. Given a orientation, we compute the Digitally Reconstructed Radiograph (DRR) according to the rule of ray-casting and compare with Digital Video Fluoroscopy (DVF) by measure the similarity index. Several similarity indices are applied, for example, mutual information, normalized cross-correlation. The optimal parameter set is the one producing the largest similarity index. 


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